Detalhe da pesquisa
1.
Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda.
N Engl J Med
; 389(8): 722-732, 2023 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-37611122
2.
Seasonal Malaria Chemoprevention Drug Levels and Drug Resistance Markers in Children With or Without Malaria in Burkina Faso: A Case-Control Study.
J Infect Dis
; 228(7): 926-935, 2023 10 03.
Artigo
Inglês
| MEDLINE | ID: mdl-37221018
3.
Decreased Susceptibility to Dihydrofolate Reductase Inhibitors Associated With Genetic Polymorphisms in Ugandan Plasmodium falciparum Isolates.
J Infect Dis
; 225(4): 696-704, 2022 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-34460932
4.
Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors.
Antimicrob Agents Chemother
; 66(10): e0081722, 2022 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-36094216
5.
Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda.
J Infect Dis
; 223(6): 985-994, 2021 03 29.
Artigo
Inglês
| MEDLINE | ID: mdl-33146722
6.
Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates.
Antimicrob Agents Chemother
; 65(10): e0077121, 2021 09 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34339273
7.
Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum.
Malar J
; 20(1): 292, 2021 Jun 30.
Artigo
Inglês
| MEDLINE | ID: mdl-34193148
8.
Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda.
Antimicrob Agents Chemother
; 63(3)2019 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30559133
9.
Modeling Prevention of Malaria and Selection of Drug Resistance with Different Dosing Schedules of Dihydroartemisinin-Piperaquine Preventive Therapy during Pregnancy in Uganda.
Antimicrob Agents Chemother
; 63(2)2019 02.
Artigo
Inglês
| MEDLINE | ID: mdl-30530597
10.
Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.
J Infect Dis
; 216(8): 1008-1017, 2017 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28968782
11.
Altered Plasmodium falciparum Sensitivity to the Antiretroviral Protease Inhibitor Lopinavir Associated with Polymorphisms in pfmdr1.
Antimicrob Agents Chemother
; 61(1)2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27821443
12.
Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity.
Antimicrob Agents Chemother
; 60(10): 5649-54, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27401569
13.
Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase.
Antimicrob Agents Chemother
; 60(8): 4886-95, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27270277
14.
Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from ugandan children.
Antimicrob Agents Chemother
; 59(6): 3018-30, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25753626
15.
Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline.
Microbiol Spectr
; 11(3): e0523622, 2023 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37158739
16.
Compounds from Sorindeia juglandifolia (Anacardiaceae) exhibit potent anti-plasmodial activities in vitro and in vivo.
Malar J
; 11: 382, 2012 Nov 21.
Artigo
Inglês
| MEDLINE | ID: mdl-23171238
17.
Computer-aided drug design of falcipain inhibitors: virtual screening, structure-activity relationships, hydration site thermodynamics, and reactivity analysis.
J Chem Inf Model
; 52(3): 696-710, 2012 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-22332946
18.
Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda.
Nat Commun
; 13(1): 6353, 2022 10 26.
Artigo
Inglês
| MEDLINE | ID: mdl-36289202
19.
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel.
Pharmaceutics
; 14(7)2022 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-35890267
20.
Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.
J Chem Inf Model
; 51(4): 852-64, 2011 Apr 25.
Artigo
Inglês
| MEDLINE | ID: mdl-21428453